A specialist in precipitation, Knight focuses on the formation of rain, hail, and snow in clouds. He is also interested in nucleation, a process by which water molecules clump together, which can lead to snow and rain formation in the atmosphere. More recently, Knight has delved into biological antifreezes, trying to understand how certain natural compounds help some species survive in freezing conditions. Knight’s research has taken him to the tropics, where he has studied the processes by which trade wind cumulus clouds generate warm rain. He has taken part in weather modification projects that seek to suppress hailstorms. Knight is also knowledgeable about artificial snowmaking.